...Retinoic acid binds to all three kinds of retinoid receptors: alpha, beta, and gamma. It is thought that the gamma receptor is the most important in the pathogenesis of acne, and retinoic acid has a very high affinity for gamma receptors. First of all, there is sebum. Sebum itself might be comedogenic, but whether it is or not, it certainly provides the nutrient material for P acnes. The proliferation of this microorganism is the next pathogenic factor. ...»
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«...Other effective natural acne remedies are tomatoes, lime juice and lettuce. Tomatoes work well on small patches of acne. Cut a ripe tomato in half length-wise. Place the inside, wet portion on your face. Leave for about an hour then rinse. Boil half a glass of milk and let cool. Add same amount of juice. Make sure mixture has cooled before applying to face. Soak lettuce for two hours in water Apply to the skin as a rinse....»
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